Carrick Institute

Clinical Neurochemistry & Nutrition Series On-Demand Prepayment PLUS Bonus Course!

$6,450.00

This 7-course bundle for the Clinical Neurochemistry & Nutrition program will give you 175 hours.

You get to choose your bonus course below!

You will have one year of access for each course, for credit. Upon purchase,  the first module will be added to your account. When ready for the next module, contact us to add it for you.

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Benefits of the Neurochemistry and Nutrition Program

  • All recommendations are based on published literature and clinical experience supporting your evidence based practice.
  • No disclosures.
  • Brand neutral. This program was designed to teach you exactly what will help your patients using a broad spectrum of nutriceuticals from multiple sources.
  • Dr. Clark is a full-time solo practitioner, with a very successful practice who’s treatment protocols are evidence based and have been tested on the field.  He has worked with a wide range of neurological, endocrine and immune system problems with consistent and reproducible results.
  • Practice management – In addition to learning which protocols will help your patient best, also learn from the instructor how a true functional medicine clinic (structural care + neurological care + nutrition) is implemented as a cash practice with a logistical and methodical implementation plan that you can begin to implement into your practice right away.
  • Generate another revenue stream in an ethical manner.  On average, the instructor distributes $25,000/month of supplementation from various companies using protocols that genuinely help patients.
  • Attendees will be taught a way to think, understand & apply neurochemistry and nutrition for their patients, rather than pathways or protocols to memorize.
  • This program series will focus on natural, non-pharmacological methods that are within your scope of practice.
  • Case-based learning…this is practice for the real world.
  • Each module will provide actionable, implementable intake, diagnostic and treatment procedures that you can begin using immediately.

Clinical Neurochemistry & Nutrition Program Outline

Module 1 – The 4 Neurochemical Priorities and Brain Basics

  • How to Use This Course
  • The 4 Neurochemical Priorities (never get lost!)
  • The Road map
  • Logistics of lab assessment
    • How to order labs
    • Who pays for labs?
  • Blood Tests and Codes for this Module
    • CBC
    • Phosphorus
    • Comp Metabolic Panel
    • Magnesium
    • Hemoglobin A1c
    • LDH
    • GGT
  • How to Work Up a Real Patient
  • Every Case Study details the patient’s presentation, work up, treatment plan and follow up.
  • Case Study – 17 year old female with headaches, fatigue, neck/back pain
  • The 10 Core Principles
  • What Does a Brain Do?
    • Global view of Brain function and purpose
    • A primer on the  evolutionary development of brain structure and function
  • Structural Components of the CNS – Brain macrostructure
  • Concepts of Neuron Structure & Function
    • How Neurons Work – Thresholds and Potentials
    • Neurotransmission, Transmitters and Receptors
      • Dopamine
      • GABA
      • Serotonin
      • Acetylcholine
    • NMDA Receptors, Glutamate and Long-Term Potentiation
    • Transneuronal Degeneration and Diaschisis
    • The DARK Side of NMDA Receptors (creepy!)
      • Excitotoxicity – what promotes it and what inhibits it
    • Synaptic Integration
  • Case Study – 27 year old woman with agitation and delirium
  • Clinical Point on Ions
    • sodium, potassium, calcium
  • Glial Cells
    • Macroglia
      • Focus on Astrocytes
      • Clinical Point on Aquaporins
      • Oligodendrocytes and Schwann Cells
    • Microglia
      • Normal role and pathophysiological role
  • Blood-Brain Barrier
    • Neurovascular unit aka Gliovascular Unit
    • What crosses and what doesn’t
  • Membranes and Lipids
  • Clinical Point on CoQ10 and Statin Drugs
  • Case Study – 65 year old male with high cholesterol
  • A Statin Alternative that actually works
  • Amyotrophic Lateral Sclerosis
    • When is ALS not ALS?
    • A reasonable evidence-based approach to ALS
  • Energy Metabolism in the Brain -glycolysis and oxidative phosphorylation
  • Stroke
    • What happens to energy production during and after stroke?
    • Stroke-induced inflammation
    • The Stroke-Migraine Continuum
  • Epilepsy
    • Pathophysiology
    • Nutritional and Metabolic Factors to consider in Epilepsy
    • The Ketogenic Diet for Seizures
    • How to work up, manage and treat a patient with Seizures.
  • Case – 10 year old girl with irritability, ADHD and recent seizure
  • Case – 16 year old girl with Hashimoto’s, Brain Fog and Vomiting
  • Case – 39 year old man with Seizures, dizziness and depression
  • Case – 64 year old woman with concerns about her Hemoglobin A1c and Lipids
  • Understanding Blood Chemistry – For each test:
    • What physiology is actually being tested?
    • What makes it high?
    • What makes it low?
    • What are the lab reference ranges?
    • What is the functional/optimal ranges?
      • Comp. Metabolic 14 PLUS
        • Glucose
        • Calcium
        • Protein
        • Albumin
        • Globulin
        • Sodium
        • Potassium
        • Chloride
        • Carbon Dioxide
        • Anion Gap
        • BUN
        • Creatinine
        • eGFR
        • Phosphorus
        • Alkaline Phosphatase
        • ALT
        • AST
        • GGT
        • Bilirubin
    • Hemoglobin A1c
    • Lactate Dehydrogenase
  • Special Section on Magnesium
    • Normal roles in physiology
    • Testing
      • What makes it high?
      • What makes it low?
    • Magnesium in Migraine
    • Magnesium in Stroke
    • Magnesium in Chronic Pain
  • Pattern Analysis of Blood Test Results
  • Case – 63 year old man with hypertension, diabetes, edema and fatigue
  • Case 66 year old woman with Diabetes and phospholipid antibodies
  • More Blood Test results scenarios
Module 2 –  Energy Production: RBC physiology, Mitochondria and Related Nutrients
  • How to Use This Course
  • The 4 Neurochemical Priorities (never get lost!)
  • The Road map
  • How to Work Up a Real Patient
  • The 10 Core Principles
  • Module 1 Review
    • Myelination and Microbiota
    • Magnesium and Depression
    • Excitotoxicity and Glutamate
    • How to handle a patient with seizures
    • Key points about ALS
    • Functional/Optimal Lab Ranges so far
  • Preview of Celiac Disease and Non-Celiac Wheat/Gluten Sensitivity
  • Preview of Parkinson’s Disease
  • Every Case Study details the patient’s presentation, work up, treatment plan and follow up.
  • Case Study – 48 year old woman with fatigue, chronic frequent dry cough
  • Blood Tests and Codes for this Module
    • CBC / Differential with Platelet Count
    • Iron
    • IBC
    • Serum Ferritin
    • Serum Methylmalonic Acid
    • Homocysteine
    • Serum Vitamin B12
    • Serum Folic Acid
    • Hereditary Hemochromatosis, DNA Analysis
    • cardiac CRP (or High sensitivity CRP)
    • H. Pylori Urea Breath Test
    • Helicobacter pylori Antibodies, IgA, IgG, IgM
    • Helicobacter pylori Stool Antigen
    • Intrinsic Factor Antibodies
    • Gastric Parietal Cell Antibodies
  • Module 2 Tests Functional/Optimal Ranges
  • Big Picture of the  Neurochemical Priorities
    • #2 – Cellular Energy: RBCs, Nutrients, MItochondria
    • #3 – Cellular Energy: HPA Axis and Glucose Handling
  • Lab Reference Ranges vs. Functional/Optimal Ranges
    • What’s the difference?
  • Energy Production in the Body
    • Citric Acid Cycle and Nutrient Co-factors
  • Physiology of Red Blood Cells
  • Understanding Blood Chemistry – For each test:
    • What physiology is actually being tested?
    • What makes it high?
    • What makes it low?
    • What are the lab reference ranges?
    • What is the functional/optimal ranges?
      • RBC
      • Hemoglobin
      • Hematocrit
      • MCV
      • MCH
      • MCHC
      • RDW
      • Platelet count
      • Reticulocyte count
    • CBC Red Blood Cell markers interpretation
      • Anemia Classifications
  • Iron Physiology
  • Iron Testing
    • What physiology is actually being tested?
    • What makes it high?
    • What makes it low?
    • What are the lab reference ranges?
    • What is the functional/optimal ranges?
      • TIBC
      • UIBC
      • Serum
      • Transferrin Saturation
      • Ferritin
  • Iron deficiencies
    • Physical signs and symptoms
    • Iron deficiency and the brain
    • Causes of iron deficiency
  • Work up for Iron deficiency and Iron deficiency anemia
  • Treatment of Iron Deficiency and Iron deficiency anemia
  • Hemochromatosis
  • Iron Supplementation
    • How much, what kind and when to take it
  • B12 Physiology
    • Absorption
  • B12 Testing
    • the problem with the serum B12
    • Methyl Malonic Acid
  • Metabolic B12 Deficiency
  • Causes of B12 Deficiency
  • What causes High levels of B12?
  • Signs, Symptoms and Effects of Low B12
  • B12 Lab testing interpretation
  • B12 Supplementation
    • What kinds, how much and when
  • Case Study- 68 year old woman with Parkinson’s
  • Case Study – 62 year old woman with depression and dysautonomia
  • Folate Physiology
  • Testing for Folate status
    • Serum Folate
  • Effects of low folate
  • Causes of low folate
  • Folate supplementation
    • how much, what kind of and when to take it
  • Homocysteine and Remethylation
    • Causes of high homocysteine
    • MTHFR
    • Homocysteine and Depression, Bipolar, Schizophrenia, Parkinson’s, Alzheimer’s Disease
    • Testing for homocysteine
    • Treatment of high homocysteine
  • Interpreting patterns of RBC markers, Iron, B12, MMA, Folate and Homocysteine
  • Effects of Iron Deficiency Anemia
  • Case Study – 25 year old woman with hemiparesthesia, blurry vision and dysautonomia
  • Case Study – 64 year old man with Parkinson’s
  • RBC Patterns on blood chemistry
  • Anemias—there’s lots of them
  • Treating underlying causes of an anemia
  • Case Study – 42 year old woman with fatigue and depression
  • Case Study – 29 year old woman with mental sluggishness, fatigue, insomnia
  • Case Study – 38 year old woman with anxiety and heart palpitations
Module 3 –Glucose Regulation, HPA Axis, Gastrointestinal System and Liver
  • The 4 Neurochemical Priorities (never get lost!)
  • The Road map
  • How to Work Up a Real Patient
  • The 10 Core Principles
  • Gastrointestinal Big Picture
  • Review of Modules 1 and 2 through analysis of ELEVEN different real-life cases.
  • Review of Functional/Optimal ranges from Module 1 and 2
  • Glucose Regulation
  • Hormones 101
  • HPA Axis and Adrenal Function
  • Adrenal Glands – Anatomy and Physiology
    • Pregnenolone
    • DHEA
    • Cortisol
  • Glucose Regulation – Insulin, HPA and the Liver
  • Assessing Adrenal Function (the real way)
    • Dynamic Tests
    • Serum DHEA-s
    • Cortisol testing
      • Salivary
      • Urinary
  • Adrenal Insufficiency
    • Addison’ Disease
    • TBI and HPA/Adrenal Function
  • Adrenal Fatigue – does it exist?
  • Overtraining Syndrome – it’s not just for athletes
  • Cushing’s Disease
  • HPA/Adrenal Treatment
    • Lifestyle
    • Supplementation
      • Adaptogens and how to use them
      • And more…
    • Exercise
    • Stress Reduction
  • Peripheral Glucose Regulation
    • C-peptide and insulin
  • Insulin Resistance
    • Causes of insulin resistance
    • Effects of insulin resistance in the brain
  • Hypoinsulinemia
  • Type 2 Diabetes
    • pathophysiology
  • Hypoglycemia
  • Reactive Hypoglycemia
  • Hypoglucocytosis
  • Glucose Regulation and Autoimmunity
    • Cross Reaaction
  • Type 1 Diabetes
    • Latent Autoimmune Diabetes of the Adult
    • Antibody testing
  • Lab Diagnosis of hyperglycemia
  • Lab Diagnosis of hypoglycemia
  • Glucose Regulation Treatment
    • Therapeutic Targets – what are you shooting for?
  • Diet for hyperglycemia modulation
    • Therapeutic Fasting – how to do ti
  • Supplementation for Glucose Regulation
    • What to use, how much and when to take it
  • Every Case Study details the patient’s presentation, work up, treatment plan and follow up.
  • Case Study – 30 year old woman with Hashimoto’s, depression, anxiety, fatigue
  • Case Study – 14 year old boy with headaches, fatigue and dizziness
  • Gastrointestinal Physiology
    • Digestion
    • Absorption
    • Elimination
    • How to use GI symptoms to triangulate the location of the problem
    • Intestinal Barrier- Anatomy and Function
      • Tight Junctions, Zonulin, Occludin
    • Gut Permeability
    • Hyper-leaky gut
  • SIBO
  • Inflammatory Bowel Disease
  • Support strategies for integrity of the gut barrier
  • Liver physiology
    • Normal Biotransformation
    • Xenobiotics
    • Toxicants
  • How to improve liver function
  • Blood tests for assessing liver function
  • Gluten
    • What is it?
    • What does it do?
  • Celiac Disease
    • Pathogenesis
    • Clinical Features and Manifestations
    • Diagnosis
  • Non-Celiac Gluten/Wheat Sensitivity
  • Testing for Celiac and NCGWS
    • Deep dive into wheat proteome and related markers
  • Gluten-related disorders
  • FODMAPS
    • Low FODMAPS Diet
  • The Anti-Inflammatory Repair Diet
    • What’s allowed, what’s not allowed and why
  • Testing for Food Sensitivities
    • What does it really mean?
    • What are you really testing?
  • Case Study – 38 year old male with fatigue and elevated transaminases
  • Case Study – 64 year old woman with increasing Hemoglobin A1c
  • Case Study – 66 year old woman with chronic diarrhea and fatigue
  • Case Study – 10 year old girl diagnosed with Multiple Sclerosis
Module 4 –Gut Part 2, The Immune System and Autoimmunity
  • The 4 Neurochemical Priorities (never get lost!)
  • The Road map
  • How to Work Up a Real Patient
  • The 10 Core Principles
  • Review of Modules 1, 2 and 3 through analysis of SEVEN different real-life cases.
  • Review of Functional/Optimal ranges from Module 1 and 2
  • Schematic view of the Immune System
    • Barriers
    • Acute Phase Response
    • Innate Immune System
    • Adaptive Immune System: T cells, B cells and more
    • Cytokines
    • Immunoglobulins, Antibodies and Isotypes
  • How the Immune System Works
  • Challenges for the Immune System: Discrimination, Flexibility, Managing Infection, Memory
  • Antibody Generation, T Cell Receptors
  • Autoimmunity
  • Lab testing: WBC and Differential, C-Reactive Protein/hs CRP, Vitamin D
  • Microbiome/Microbiota
    • Microbiota-Gut-Brain Concepts
    • Microbiota-Gut-Brain-Immune Axis
    • Short chain fatty acids and their clinical applications
    • Dendritic Cells
    • Induction of Treg cells
    • Effects of Antibiotics
    • Ectopic Colonization
  • Intestinal Permeability Revisited: Tight Junctions
  • Gut Barrier and Blood-Brain Barrier
  • Feeding Microbiota and Protecting the Barrier
  • Autoimmunity…the Deep Dive
    • Pre-requisites
    • Clinical Presentations
  • Food Antigens and the Immune System
    • Oral Tolerance
    • Cross-reactivity
    • Food Sensitivity Testing: the good news and bad news, and the really bad news
  • Testing for clinically significant autoimmunity
    • Clinical Immune System Challenge: the rules and how to interpret
    • Predictive Antibody testing
      • Survey of common antibody tests and what they mean clinically
  • Type 1 Diabetes
  • Celiac Disease
  • Regulating the Immune System with Diet, Exercise and Supplementation
  • The Anti-inflammatory Diet
  • Anti-inflammatory/Immune Regulatory Supplementation
  • Case Study – 60 year old woman with bone loss throughout her body
  • Case Study – 55 year old woman Rheumatoid Arthritis
  • Case Study – 20 year old man with brain fog, low motivation, low energy, lack of focus and low affect
  • Case Study – 15 year old boy with muscle fatigue, joint pain, migraines, brain fog and balance deficits
  • Case Study – 19 year old male with irritable bowel syndrome, ADD and Autism
  • Case Study -10 year old girl with pediatric Multiple Sclerosis
Module 5 – Neuroimmunology, Vestibular Conditions and Neuropsychiatric Conditions
  • The 4 Neurochemical Priorities (never get lost!)
  • The Road map
  • How to Work Up a Real Patient
  • The 10 Core Principles
  • Cases to reinforce previous 4 modules
  • Review of Module 4
  • New immune system test: The Lymphocyte MAP Immunophenotyping Test
    • Analysis and explanation of the 13 Immunophenotypes
  • Why order a Lymphocyte MAP?
  • Review of Modules 1 – 4 using 13 different REAL clinical cases
  • Current Topics: Tics and COVID-19, Adverse Childhood Experiences and Neurologic Disease, Vitamin D and SARS Cov-2, Statins and Diabetes progression
  • Sleep
  • Normal physiology including stages and Melatonin
  • Abnormal sleep patterns
  • Sleep hygiene
  • Sleep Scenarios
  • Acute Pain Relief
  • Pain—in general and in specific clinical conditions
    • The NLRP3 Inflammasome
    • Autoimmunity and Pain
  • Complex Regional Pain Syndrome
  • Case Study – 29 year old woman with CRP and two spinal cord stimulators
  • Fibromyalgia – short and sweet
  • Peripheral Neuropathy – overview (there’s a separate course on PN)
  • Case Study – 64 year old woman with REM Sleep Behavior Disorder
  • Vestibulo-Cochear System and Disorders
  • Labyrinthine physiology including the Blood-Labyrinth Barrier
  • Inner Ear Immune System
  • Vertigo
  • How does the immune system affect the Vestibulocochlear System
  • Vertigo in Autoimmune Disorders
  • BPPV: causes and treatments
  • Vitamin D and BPPV
  • Thyroid, BPPV and recurring BPPV
  • Recurrent BPPV Treatment
  • Meniere’s Disease
  • Meniere’s and Autoimmunity
  • Gluten and Meniere’s
  • Meniere’s Disease Treatment
  • Tinnitus: Definition, sources and clinical applications
  • Vestibular Migraine
  • Otolithic Vertigo
  • Mesencephalic Dizziness
  • Locus Minoris Resistentiae
  • Case Study – 53 year old man with ocular migraines, double vision and pre-syncope and vertigo
  • Case Study – 54 year old woman with hearing loss and tinnitus
  • Case Study – 62 year old man with vertigo and hearing loss
  • Case Study – 38 year old man with feelings of being on a boat and dysequilibrium
  • Case Study – 32 year old woman with dizziness, lightheadedness and vertigo
  • Case Study – 48 year old man with hearing loss due to bilateral Meniere’s disease
  • Case Study – 51 year old woman with dizziness, fatigue, dysequilibrium
  • Case Study – 24 year old woman with feeling of being on a boat, anxiety, brain fog
  • The Gut and Psychiatry
  • Major Depression Disorder:
    • inflammation, homocysteine, oxidative stress, Vitamin D, Thyroid autoimmunity, SAMe, Folate, B12, Tryptophan, probiotics, HPA, micronutrients, NAC
  • Bipolar Disorder:
    • Inflammation, thyroid autoimmunity, homocysteine, oxidative stress
  • Obsessive Compulsive Disorder
    • Autoimmunity
  • Schizophrenia
    • homocysteine, EBV, Autoimmunity, gluten-free diet, copper, lithium,
  Module 6 – Neurodegeneration, Course Review and Special Section on Patient Management
    • How to Use This Course
    • The 4 Neurochemical Priorities (never get lost!)
    • The Road map
    • How to Work Up a Real Patient
    • The 10 Core Principles
    • Big Brain Review
    • Autophagy – how to induce it
    • Mitophagy – how to induce it
    • Neuroinflammation for homeostasis
    • Neuroinflammation in CNS diseases: Parkinson’s, Alzheimer’s, Huntington’s, MS, Depression, Sleep Disorders
    • Necrosis vs. apoptosis – cell death and survival
    • Neurodegeneration: the role of the immune system, glucose, metals, mitochondria, microbiome, astrocytes, microglia, oral health, tryptophan/kynurenine, sex hormones, gluten, vitamins, NRF2
    • A short course on TBI ( an official Primer course is coming)
      • Definitions
      • Clinical presentation
      • Pathophysiology
      • Downstream effects
      • Diagnostic workup for a TBI a patient
      • How to help a patient with TBI with diet, exercise, supplementation
    • The clinical expressions of neuroinflammation and neurodegeneration
    • Sleep and Cognitive decline
    • Parkinson’s Disease: brain first type , body first type
    • Risk factors for Parkinson’s: Diet, Diabetes, Influenza, Statins, Air pollution
    • Parkinson’s Pathophysiology: alpha-synuclein, Autophagy, Tau, glutathione, Gut microbiome, immune system and inflammation, Kynurenine pathway, autoimmunity, mitochondria
    • Medical Management of Parkinson’s
    • Diet: fasting and more
    • Exercise
    • Supplementation
    • Dementia: SCD, MCI, Alzheimer’s
    • Dementia pathophysiology
    • Dementia evaluation and diagnosis
      • How to use the MOCA and SAGE
    • Alzheimer’s Disease
    • Pathological features of Alzheimer’s
    • Pathophysiology of Alzheimer’s
      • Genetics
      • APOE & Lipids
      • BDNF
      • Mitochondria and ROS
      • Autophagy and mTOR
      • Amyloid Cascade Hypothesis
      • Tau
      • Infections
      • Diabetes and Insulin Resistance
      • Sleep
      • Immune System, Inflammation and Neuroinflammation
      • Autoimmunity
      • Porphyromonas Gingivitis
      • The gut and microbiome
    • Alzheimer’s Risk Factors
      • Depression
      • Thyroid function
      • Vitamin D
      • Autoimmune Diseases
      • Coffee and Tea Consumption
      • Autonomic function
      • Physical activity
      • BMI
      • Vaccinations
    • Alzheimer’s and COVID-19
    • Medical management of Alzheimer’s
    • Frontotemporal Dementia cliff notes
    • ALS review
    • Strategies for Neurodegeneration
      • Diet, fasting and ketones
      • Exercise
      • Specific Supplementation – so much to talk about here
    • Diet interventions for Neuroinflammation and Neurodegeneration
    • Neuroprotective Strategies
    • Patient Management strategies for full implementation
    • This module serves as an excellent overview in preparation for the certification examination
Bonus Course

Mastery of Peripheral Neuropathy, Mastery of Neurochemistry of Autism Spectrum Disorders, Mastery of Neurochemistry of Male & Female Hormones, Mastery of the Thyroid-Brain Axis

Faculty

Dr. David Clark

Neurology Hours

25 Neurology Hours

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