Topic: Review & Clinical Applications of Core Concepts & Principles

• • How to Use This Course
  • The 4 Neurochemical Priorities (never get lost!)
  • The Road map
  • How to Work Up a Real Patient
  • The 10 Core Principles
  • Big Brain Review
  • Autophagy – how to induce it
  • Mitophagy – how to induce it
  • Neuroinflammation for homeostasis
  • Neuroinflammation in CNS diseases: Parkinson’s, Alzheimer’s, Huntington’s, MS, Depression, Sleep Disorders
  • Necrosis vs. apoptosis – cell death and survival
  • Neurodegeneration: the role of the immune system, glucose, metals, mitochondria, microbiome, astrocytes, microglia, oral health, tryptophan/kynurenine, sex hormones, gluten, vitamins, NRF2
  • A short course on TBI ( an official Primer course is coming)
    • Definitions
    • Clinical presentation
    • Pathophysiology
    • Downstream effects
    • Diagnostic workup for a TBI a patient
    • How to help a patient with TBI with diet, exercise, supplementation
  • The clinical expressions of neuroinflammation and neurodegeneration
  • Sleep and Cognitive decline
  • Parkinson’s Disease: brain first type , body first type
  • Risk factors for Parkinson’s: Diet, Diabetes, Influenza, Statins, Air pollution
  • Parkinson’s Pathophysiology: alpha-synuclein, Autophagy, Tau, glutathione, Gut microbiome, immune system and inflammation, Kynurenine pathway, autoimmunity, mitochondria
  • Medical Management of Parkinson’s
  • Diet: fasting and more
  • Exercise
  • Supplementation
  • Dementia: SCD, MCI, Alzheimer’s
  • Dementia pathophysiology
  • Dementia evaluation and diagnosis
    • How to use the MOCA and SAGE
  • Alzheimer’s Disease
  • Pathological features of Alzheimer’s
  • Pathophysiology of Alzheimer’s
    • Genetics
    • APOE & Lipids
    • BDNF
    • Mitochondria and ROS
    • Autophagy and mTOR
    • Amyloid Cascade Hypothesis
    • Tau
    • Infections
    • Diabetes and Insulin Resistance
    • Sleep
    • Immune System, Inflammation and Neuroinflammation
    • Autoimmunity
    • Porphyromonas Gingivitis
    • The gut and microbiome
  • Alzheimer’s Risk Factors
    • Depression
    • Thyroid function
    • Vitamin D
    • Autoimmune Diseases
    • Coffee and Tea Consumption
    • Autonomic function
    • Physical activity
    • BMI
    • Vaccinations
  • Alzheimer’s and COVID-19
  • Medical management of Alzheimer’s
  • Frontotemporal Dementia cliff notes
  • ALS review
  • Strategies for Neurodegeneration
    • Diet, fasting and ketones
    • Exercise
    • Specific Supplementation – so much to talk about here
  • Diet interventions for Neuroinflammation and Neurodegeneration
  • Neuroprotective Strategies
  • Patient Management strategies for full implementation
  • This module serves as an excellent overview in preparation for the certification examination

• 25 hours of training with Dr. David Clark
• LIFETIME access to the digital recording of the class
• Any future updates to the course videos or other materials
• Re-attendance for life – Retake the class on-site, via livestream or via online, self-paced learning as many times as you’d like for attendance hours. 
• 25 Neurology Hours towards the ACFN (American College of Functional Neurology) & ACNB (American Chiropractic Neurology Board) with each module
• Access to the flipped classroom with lifetime updates 
• 3 months of unlimited access to Medline upon completion of the module